Search Results for: breakfast circadian

Ketone bodies as signaling metabolites

*non sequiter* One of the ways dietary carbohydrate contributes to liver fat is via ChREBP: “carbohydrate-response element binding protein.”  It responds to a glucose metabolite and activates transcription of lipogenic genes.  Insulin helps.  Ketones do the opposite (Nakagawa et al., … Continue reading

Sweet’n Low

I didn’t want to blog about the artificial sweetener study; to be honest, I didn’t even want to read it.  I just wanted to report: 1) how many Diet Cokes are we talking about; and 2) when are you going … Continue reading

“Afternoon diabetes” and nutrient partitioning

Don’t exacerbate afternoon diabetes with afternoon carbs. Skeletal Muscle As discussed previously [at length], insulin sensitivity in skeletal muscle follows a circadian pattern: starts out high in the morning and wanes throughout the day. Diurnal variation in oral glucose tolerance: … Continue reading

Cyclical ketosis, glycogen depletion, and nutrient partitioning

Meal & exercise timing in the contexts of “damage control” and nutrient partitioning are frequent topics on this blog.  I generally opt for a pre-workout meal, but nutrient timing hasn’t panned out very well in the literature.  That’s probably why … Continue reading

Carb Back-Loading, take II

Brief refresher: skeletal muscle insulin sensitivity is higher in the morning than in the evening.  Exercise boosts insulin sensitivity selectively in muscle, which is relatively more important in the evening.  Thus, an evening carb-load may benefit from exercise to effectively partition … Continue reading

Skipping meals, intermittent fasting, grazing, etc.

or… Circadian Meal Timing! They say if you’re going to [intentionally] skip a meal, it should be breakfast – and hey, that’s probably the easiest meal to skip.  However, a recent study showed skipping dinner FTW (well, not exactly).  I’ve never seen a … Continue reading

On resistant starch and blood glucose control

For overall health and well-being, fermented foods like sauerkraut and kefir are great.  Especially when following a low carbohydrate diet which is generally low in the types of foods which feed the gut microbiome. For those with gastrointestinal problems, the … Continue reading

PODCASTS

Counting calories to lose weight does not work for the majority of dieters. This happens, in part, because the calories in food are not the same as those expended by the body. This book is intended to explain this misperception, … Continue reading

Pocket Guide to Intermittent Fasting

Intermittent Fasting (IF) is all the rage these days, and there are a variety of different protocols out there, pioneered by people ranging from Ori Hofmekler (The Warrior Diet), Kate Harrison (The 5:2 Diet), Michael Mosley (The Fast Diet), Bert … Continue reading

Missing: 300 kilocalories

or Weight-loss maintenance, part II (as promised) Effects of dietary composition on energy expenditure during weight-loss maintenance (Ebbeling et al., 2012) A three-way crossover study!  Excellent study design.  In brief, the participants lost 30 pounds in 12 weeks on a … Continue reading