PUBLICATIONS: Her TK, Lagakos WS, Brown MR, LeBrasseur NK, Rakshit K, Matveyenko AV. (2020) Dietary carbohydrates modulate metabolic and beta-cell adaptation to high-fat diet-induced obesity. American Journal of Physioogy, Endocrinology and Metabolism 1;318(6)E856-E865.
Chen K, Jih A, Kavaler ST, Lagakos WS, Oh D, Watkins SM, Kim JJ. (2015) Dual actions of a novel bifunctional compound to lower glucose in mice with diet-induced insulin resistance. American Journal of Physiology, Endocrinology, and Metabolism 1;309(3):E293-301.
Li P, Oh da Y, Bandyopadhyay G, Lagakos WS, Talukdar S, Osborn O, Johnson A, Chung H, Mayoral R, Maris M, Ofrecio JM, Taguchi S, Lu M, Olefsky JM. (2015) LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes. Nature Medicine Mar;21(3)239-47.
Rothschild J, Lagakos W. (2015) Implications of enteral and parental feeding times: considering a circadian picture. Journal of Parenteral and Enteral Nutrition Mar;39(3)266-70.
Oh DY, Walenta E, Akiyama TE, Lagakos WS, Lackey D, Pessentheiner AR, Sasik R, Hah N, Chi TJ, Cox JM, Powels MA, Di Salvo J, Sinz C, Watkins SM, Armando AM, Chung H, Evans RM, Quehenberger O, McNelis J, Bogner-Strauss JB, Olefsky JM. (2014) A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice. Nature Medicine 20(8):942-7.
Inokuchi-Shimizu S, Park EJ, Roh YS, Yang L, Zhang B, Song J, Liang S, Pimienta M, Taniguchi K, Wu X, Asahina K, Lagakos W, Mackey MR, Akira S, Ellisman MH, Sears DD, Olefsky JM, Karin M, Brenner DA, Seki E. (2014) TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis. Journal of Clinical Investigation 124(8):3566-78.
Lu M, Li P, Bandyopadhyay G, Lagakos W, Dewolf WE Jr, Alford T, Chicarelli MJ, Williams L, Anderson DA, Baer BR, McVean M, Conn, Veniant MM, Coward P. (2014) Characterization of a novel glucokinase activator in rat and mouse models. PLoS One 9(2):e88431.
Li P, Spann NJ, Kaikkonen MU, Lu M, Oh da Y, Fox JN, Bandyopadhyay G, Talukdar S, Xu J, Lagakos WS, Patsouris D, Armando A, Quehenberger O, Dennis EA, Watkins SM, Auwerx J, Glass CK, Olefsky JM. (2013) NCoR Repression of LXRs Restricts Macrophage Biosynthesis of Insulin-Sensitizing Omega 3 Fatty Acids. Cell 155(1):200-14.
Lagakos WS, Guan X, Ho SY, Sawacki LR, Corsico B, Kodukula S, Murota K, Stark RE, Storch J. (2013) Liver fatty acid-binding protein binds monoacylglycerol in vitro and in mouse liver cytosol. Journal of Biological Chemistry 288(27):19805-15.
Lee YS, Morinaga, Kim JJ, Lagakos W, Taylor S, Keshwani M, Perkins G, Dong H, Kayali AG, Sweet IR, Olefsky J. (2013) The fractalkine/CX3CR1 system regulates b cell function and insulin secretion. Cell 153(2):413-25.
Bae EJ, Xu J, Oh DY, Bandyopadhyay G, Lagakos WS, Keshwani M, Olefsky JM. (2012) Liver-specific p70 S6 kinase depletion protects against hepatic steatosis and systemic insulin resistance. Journal of Biological Chemistry 287(22):18768.
Lagakos WS. The poor, misunderstood calorie. Charleston: Createspace, 2012.
Oh D, Lagakos WS. (2011) The role of GPRs in mediating the effect of fatty acids on inflammation and insulin sensitivity. Current Opinion in Clinical Nutrition and Metabolic Care 14(4):322-7.
Lagakos WS, Gajda AM, Agellon L, Binas B, Choi V, Mandap B, Russnak T, Zhou YX, Storch J. (2011) Different functions of intestinal and liver-type fatty acid-binding proteins in intestine and in whole body energy homeostasis. American Journal of Physiology 300(5):G803-14.
Manso Filho HC, McKeever KH, Gordon ME, Manso HE, Lagakos WS, Wu, G, Watford M. (2009) Developmental changes in the concentrations of glutamine and other amino acids in plasma and skeletal muscle of the Standardbred foal. Journal of Animal Science 87(8):2528-35.
Manso Filho HC, McKeever KH, Gordon ME, Costa HE, Lagakos WS, Watford M. (2008) Changes in glutamine metabolism indicate a mild catabolic state in the transition mare. Journal of Animal Science 86(12):3424-31.
Storch J, Zhou YX, Lagakos WS. (2008) Metabolism of apical versus basolateral sn-2-monoacylglycerol and fatty acids in rodent small intestine. Journal of Lipid Research 49(8):1762-9.
Neeli I, Siddiqi SA, Siddiqi S, Mahan J, Lagakos WS, Binas B, Gheyi T, Storch J, Mansbach CM 2nd. (2007) Liver fatty acid-binding protein initiates budding of pre-chylomicron transport vesicles from intestinal endoplasmic reticulum. Journal of Biological Chemistry 282(25):17974-84.