Bimagrumab: an elusive potential inhibitor of myostatin (the muscle blocker)
Miragrebon: a beta-3 agonist, fueler of BAT thermogenesis
Tl;dr: both work. In addition to tirzepatide (or its subordinate, semaglutide), exercise in a [poly]pill may have arrived…… including UPF-free #eTRF if you are so inclined or striving for #Optimal™ jk 🙂
Effect of Bimagrumab vs Placebo on Body Fat Mass Among Adults With Type 2 Diabetes and Obesity: A Phase 2 Randomized Clinical Trial (Heymsfeld et al., 2021)
Tl;dr: we weren’t wrong about myostatin, we just didn’t have the right tools to influence it. Now, we do.
Next time someone says you can’t gain muscle and lose fat at the same time, here’s another example proving them wrrrongo (pronounced with a rolling “r”):
For the rest of this article and more, head over to Patreon! Five bucks a month for access to this and all previous articles. 16% off for annual subscriptions! It’s ad-free and you can cancel if it sucks ?
For personalized health consulting services: firstname.lastname@example.org.
Affiliate links that probably don’t work anymore: OMAHA. STEAKS. Check here for daily discounts and the best steaks of your life.
Still looking for a pair of hot blue blockers? TrueDark is offering 10% off HERE and Spectra479 is offering 15% off HERE. Use discount code LAGAKOS for a deal on CarbonShades. If you have no idea what I’m talking about, read this then this.
Naked Nutrition makes some great products, including Naked Grass Fed Protein. Also, free shipping
20% off some delish stocks and broths from Kettle and Fire HERE.
Real Mushrooms makes great extracts. 10% off with coupon code LAGAKOS. I recommend Lion’s Mane for the brain and Reishi for everything else.