Circadian alterations in patients with neurodegenerative diseases: neuropathological basis of underlying network mechanisms (Fifel and Videnovic, 2020)
Spoiler alert: sunlight and good sleep are primo here. Sure, exercise and maintaining a healthy body weight are important, but the links between circadian arrhythmia and neurodegenerative diseases are very compelling.
Evidence is multi-fold: assessing cortisol & melatonin rhythms in patients and their 1st degree relatives, cell culture studies on patient’s cells, post-mortem analysis of brain tissue, sleep/actigraphy studies, etc., etc.
I know what you’re thinking: cancer, heart disease, diabetes, asthma, and now this?!
Non-diet tips: 1) sunrise; 2) wear blue blockers. Every. Night; 3) good sleep.
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Get some dark chocolate, too