Monthly Archives: September 2011

Empty calories V

The final horcrux!  Empty calories induce a feed-forward loop that promotes  over-consumption. … the following evidence is indirect, of course, but very compelling.

Food intake measured by an automated food-selection system: relationship to energy expenditure (Rising, Ravussin, et al., 1992 AJCN)

This study was designed to validate a new technique for measuring food intake; it had nothing at all to do with “empty calories.”

10 lean, healthy young men.  During a 4-day run-in period, the amount of calories required to maintain energy balance was measured with extreme precision.  Then for 7 whole days, they lived in a metabolic ward and dined from … wait for it … “vending machines.”

 

The vending machines were loaded with entrees, snacks, and beverages, [sic]: “familiar and preferred foods,” aka a “cafeteria diet.”  And I was delighted to see they also published the menu:

 

This study fit so perfectly because the Empty Calories series’ singular major thesis is: empty calories promote over-consumption.  And this can be tested by examining the two logical extremes: 1) a diet devoid of empty calories is inherently healthier, and any increase in the amount of empty calories consumed is accompanied with a decrease in health outcomes; and 2) eating more empty calories will not be balanced by eating less of something else, because empty calories are nutritionally bankrupt and do not affect satiety proper.  And this menu, oh yes, is almost entirely empty calories.

The researchers purposely filled the vending machine with individually packaged processed foods because of their convenience; it’s a very easy way to measure food intake, which was the focus of their study.

The following figure is absolutely nuts; you couldn’t make this stuff up.  like it was mathematically designed to support the Empty Calories credo.

 

It started immediately on day 1 of “ad libitum intake;” food intake doubled- the food was so nutrient poor that twice as many calories were necessary to satisfy their appetite.

Where did all those excess “empty calories” go?  Some (~17%) were spontaneously burned off (increased 24h EE) but most were invested in the infamous negative-yield* calorie savings banks (i.e., adipose).  [*you don’t get back more than you invested].

 

Side note: check the numbers, an overconsumption of 10975 kJ/d = 2622 kcal.  For 7 days = 18,353 kcal; which is approximately the amount of energy in 5.2 pounds (2.4 kg) of fat tissue.  They gained 2.3 kg, just a hair less than mathematically predicted (so much for spontaneously burning off 17% of the excess).  Body composition was not measured, but given the huge increase in carbohydrate intake, I imagine insulin levels were through the roof driving all of the excess energy into fat mass.

This has been confirmed numerous times.  For example, Larsen et al. (1995):

 

When fed the “cafeteria diet” from vending machines, these women almost doubled their food intake and gained a full pound of fat in under a week.  But I digresss.

“And this can be tested by examining the two logical extremes: 1) a diet devoid of empty calories is inherently healthier, and any increase in the amount of empty calories consumed is accompanied with a decrease in health outcomes; and 2) eating more empty calories will not be balanced by eating less of something else, because empty calories are nutritionally bankrupt and do not affect satiety proper.”

The second postulate has been addressed and sufficiently supported by Ravussin’s vending machine study (above).  Fortunately for us a study that addressed the first postulate was blogged on previously.

 

Remember now?

(Hashim and Van Itallie, circa 1965)

 

When fed a bland yet nutritionally complete diet, obese subjects spontaneously and drastically reduced their food intake, and body weight plummeted for EIGHT STRAIGHT MONTHS.  Although this was confirmed a decade later by Cabanac and Rabe (1976), it only indirectly supports the first postulate because it was not real food.  But it proves the point that nutrient sufficiency supports satiety, and this can be dissociated from total calorie intake.  IOW, if the diet provides the essential nutrition, then the remaining daily energy requirement can be met by burning excess fat mass stored in adipose tissue.

avoid ‘empty calories’ and cash out

 

calories proper

 

 

 

 

Empty calories IV

Welcome to the fourth installment, empty calories in everyday life

on feeling “full”

fullness can be manipulated by a variety of things, but never truly fooled.  Try drinking a fiber-rich beverage (e.g., Metamucil) right before mealtime and then eat slowly… you will feel full much sooner.  This may even cause you to eat less, but it won’t last … it’s not an effective long-term weight loss or weight maintenance strategy.  and it might even do harm… fiber makes you feel fuller faster by expanding (absorbs water) in your GI tract- it will stretch out your stomach a bit.  When you run out of it, or decide enough is enough, your stomach will feel emptier than usual, which will increase the amount of food necessary to make you feel “full.”

In the example above, that fiber drink would be considered to have a very low energy density.

on energy density

“Energy density” is bunk.  Ha!

But really, advising someone to consume a “low energy density” diet is wrong.  The rationale underlying “low energy density” diets is that fat, the macronutrient, contains 9 calories per gram, whereas carbohydrates only have 4, less than half.  Thus, there is >2x the amount of energy contained in a gram of fat than in a gram of carbs, i.e., fat is more energy dense.  However, when it comes to real food (food, not macronutrients), things change.  E.g., crackers are promoted as a healthy snack for low energy density dieters because crackers are very low fat (4% by weight) and thus low energy dense.  Red meat, on the other hand, has a high energy density (fat content 20-30% by weight)…  but wait, are those statistics referring to macronutrients … or food?

100 grams of crackers can have anywhere from 393 (Saltines) to 492 (Ritz) kilocalories, but 100 grams of red meat has 258 (Porterhouse) – 332 (ground beef) kcal.  Since things like water content vary widely among different foods, the energy density of macronutrients is not the same as that of the foods we actually eat.

on snacking

Think of a meat-eater you know.  Regardless of how much they love steak, they couldn’t eat it until they were sick.  But watch a little kid eating snacks, for example.  especially kids, who are more vulnerable than adults to obesogenic foods.

Most non-animal food sources (rice, pasta, beans, potatoes, etc.), including snacks, lack one or more nutrient or essential amino acid and are therefore considered nutritionally inadequate.  WRT to nutritional deficiencies: for practically every nutrient, the “at-risk for deficiency group” is almost always vegetarians (and/or alcoholics).

Snacks and plant-based foods are nutritionally incomplete; we might overeat them because of this.  Perhaps protein, EFA, & nutrient sufficiency is detected by the satiety systems in our brain.

It is difficult but not impossible to eat a nutritionally adequate vegetarian diet (sans industrial fortification), but it’s practically impossible to be nutritionally insufficient if a small variety animal foods are included in the diet (eggs, red meat, salmon, chicken, etc.)… low chance of success in the former vs. low chance of failure in the latter?

A can of Pringles has more calories than a dozen eggs (900 vs. 852 kcal).  But it’s virtually impossible to eat a dozen whole eggs, partially because that’s gross, but also possibly because just a few eggs provide more than enough nutrition to signal into the satiety system.  IOW, it’s much easier to overeat empty calories.

Snacks make people fat, in part, because they are designed to be tasty but provide little nutrition.  If snack foods provided adequate nutrition, they would satisfy our hunger and we’d eat [and buy] less.  The tasty flavors make us want and like them, and the lack of nutrition prevents us from becoming satiated.

Nutrient density FTW.

 

calories proper

 

 

 

Empty calories III

Empty calories.  Nutrient density.  Empty calories.  The ANDI score?

With the advent of the ANDI, it is safe to say the phrase, school of thought, and cult following to “a calorie is a calorie” is fading.  All calories were not created equal; some make you fat, others make you strong.  Cantankerous old biochemists and low-fat diet proponents will likely remain loyal, however, with the former citing heat production in a bomb calorimeter (mumbo), and the latter citing the equivalency of nutrient density and animal fat scarcity (jumbo).

But for the rest of us, there is gravitas in this concept       empty calories.

A good place to start might be a critical view of Fuhrman’s  Aggregate Nutrient Density Index (ANDI).  In brief, ANDI is an index of healthiness and is calculated by dividing the amount of nutrients in a given whole food by the calories.

Pro’s and con’s

1)      it only applies to whole foods.  This is convenient because most processed foods would score miserably low unless they’ve been industrially fortified with synthetic vitamin-like chemicals.  Perhaps Fuhrman restricted ANDI to whole foods because something like Diet Coke Plus would score about a million (lots of vitamins, few if any calories), rendering ANDI utterly meaningless to the masses and downright offensive to people like me.

 

2)       “nutrients per calorie” is a far more biologically meaningful and physiologically relevant concept than “calories per gram.”

  1. “Calories per gram” can be too easily manipulated.  E.g., one ounce (~28 grams) of soybean oil has 248 kilocalories: 248 kilocalories / 28 grams ? 9 kcal/g.  Add it to an ounce of water and you get 248 / 56 ? 4.4 kcal/g.  It’s still the same nutritionally, but the “caloric density” was halved by trickery.
  2. “Nutrients per calorie” is relatively unchangeable.  Let’s say there are 14 grams of omega-6 fatty acids in an ounce of soybean oil; that would be 14 grams per 248 kcal.  Add it to an ounce of water and it’s still true.  Drink it on the moon and it’s still true (relatively).

However,

1)      ANDI selectively quantifies only one aspect of a food’s nutritional value.  It is an important aspect, but please note that a diet based on high ANDI foods would be nutritionally inadequate.  Furthermore, there are highly relevant health parameters that ANDI completely ignores.  More questions:

  1. Shouldn’t more important nutrients be given a higher score?
  2. Shouldn’t excess amounts of a nutrient detract from the score?
  3. What about other non-nutritive health-promoting properties of a food?  E.g., foods that are healthier than indicated by their ANDI score:
    1. i.      foods that have some as-of-yet undiscovered nutrients
    2. ii.      foods that indirectly promote health (like pre- or pro-biotics)

2)      Furthermore, ANDI is fundamentally flawed in its application to foods whose value is based at least partially on the actual calories themselves.

  1. Fuhrman uses the ANDI score on fats, which score dismally low because they contain few “nutrients” and a lot of calories.  Thus, industrially-modified, partially-hydrogenated trans fat-rich soybean oil has the same ANDI score as olive oil.
  2. Animal proteins, including grass-fed beef, wild salmon, and pastured eggs, also score incredibly low.  These foods are far more healthful than many most others, essential for life (unlike kale, which is the highest-scoring ANDI food), and much of their value is contained in the quality of their calories.
    1. i.      the fatty acids in salmon are healthy in and of themselves; they don’t contain any nutrients per se; they ARE the nutrient.  But ANDI doesn’t take this into account; it views all fatty acids as empty calories, a grave mistake.
    2. ii.      the same goes for animal proteins.  Eggs, for example, are higher in protein quality than any other food on the ANDI scale yet they score quite low.  And getting a bio-equivalent amount of protein from lower quality plant proteins would require consuming many more calories.

The failure of ANDI to incorporate any measure of fat or protein quality is its demise; why it is unable to stand alone as an indicator of healthiness… a diet consisting exclusively of high ANDI foods is incompatible with life.  A protein deficiency would be vastly more severe than a low ANDI diet, and on a lighter note, the fish oil fatty acids would provide much greater benefits than a high ANDI diet.  These nutritional factors play too big a role in determining healthspan and quality of life to be ignored.

BUT, ANDI is nice in its simplicity, and it works very well for most plant-based foods.  E.g., spinach and cabbage have very high ANDI scores; rice, grains, and pasta have very low ANDI scores.

The diets of many cultures are based almost exclusively on low-ANDI foods.  This is largely because it is much easier to produce enough calories to feed a village than to produce enough nutrients.  Starvation is deadlier than dermatitis.  In the Western world, however, we are fighting a different battle: you need to eat a LOT of empty calories in order to get enough nutrients, but then you get fat.

 

calories proper

 

 

Empty calories, II

You should be ashamed of yourself!

Foods, fortificants, and supplements: where do Americans get their nutrients? (Fulgoni et al., 2011 Journal of Nutrition)

The Journal of Nutrition just published an analysis of micronutrient intake in healthy Americans.  The dataset came from the National Health and Nutrition Examination Survey (NHANES), which is run by the Centers for Disease Control (CDC)  and the National Center for Health Statistics (NCHS).

The USDA database was their primary source for nutrient information, but the Food and Nutrient Database for Dietary Studies (FNDSS) and Nutrient Database for Standard Reference (SR)  were also consulted when appropriate values were unavailable.  As the authors faithfully noted in the methods section, these registries are not perfect, but they really did do a lot of footwork to get accurate, up-to-date data.

Importantly, intake from whole foods, processed foods, and supplements was differentiated.  AND bioavailability was taken into account!   Kudos.

Shamefulness: over half of you are not getting enough vitamins D and E, and many are not getting enough vitamins A and C, and magnesium and calcium.

And if it weren’t for processed foods, too many of you would be consuming too little thiamin, niacin, riboflavin, and folate!  Why are you dependent on processed foods for vitamin sufficiency!?!

In the graph below, the higher the solid bars, the more people are vitamin insufficient if only whole foods are considered.  Notice that when processed foods are taken into consideration, the values are much lower for thiamin, niacin, riboflavin, and folate (open bars).  And supplements don’t add a whole lot to the picture (shaded bars).

Supplements don’t change the big picture very much because, well, who takes supplements?  Healthy people.  Healthy people who are probably already getting enough vitamins and minerals from the whole foods in their diet.  Someone who lives on fast food, soda, and crisps probably doesn’t care enough about their health to swallow a multivitamin every morning.  However, their intake is not suboptimal because they don’t take a multivitamin pill, it’s suboptimal because their diet contains too many empty calories!

TO DO: from whole food sources (i.e., not empty calories), get more:

Magnesium: spinach

Vitamin A: red meat, chicken, spinach, kale

Vitamin C: berries, broccoli, kale, peppers

Vitamin D: salmon/fish, whole eggs, red meat, liver

Vitamin E: spinach, nuts, fish

Potassium: spinach, tomatoes, beans

 

And while “adequate is adequate,” stop relying on processed foods and start eating more whole foods for:

Folate: foliage (leafy vegetables like spinach), also high in turkey, chicken, beans, etc.

Thiamin: pork, and lesser amounts in liver, whole eggs, nuts

Iron: red meat

 

processed foods are empty calories.  a processed food that has been chemically fortified with a synthetic vitamin cocktail is still “empty calories” in my book.  And although frank toxicity is rare, processed foods are close to providing too much of certain nutrients, e.g., niacin, vitamin A, folate, and zinc.  Stick to whole foods, and don’t overdo it with your kids- they were more likely than adults to be getting too much zinc, niacin, vitamin A, and folate, and the overage was largely due to processed foods.

 

Calories proper