getting a lot of emails about this study; here’s my 30000-foot view. I’ll update if the final version differs from the pre-print in any meaningful way.
Nutri-Twitter has a love/hate relationship with Dr. Kevin Hall’s research studies. Even I’ve been critical of some in the past. But he’s doing the work. Gotta be one of the most productive researchers in the field, attacking the diet wars from a variety of angles.
Our subjects likely did not increase intake on ABLC vs baseline because fat mass stayed roughly constant. As you know, answering your question was not the purpose of our study. See the penultimate paragraph below pic.twitter.com/UnrhG8RzM3
— Kevin Hall (@KevinH_PhD) May 11, 2020
Small sample size and short duration, but that’s the price you pay for an extremely well-designed and controlled study.
Main endpoint was ad lib food intake. Many people have criticized the short duration: 1) two weeks to study ad lib food intake. Many of those same people will champion SINGLE MEAL studies, effects of macronutrient-specific meals on food intake during subsequent meals. In that light, 2 weeks is above and beyond the status quo.
2) insulin, appetite, and ad lib food intake PLEASE DON’T SHOOT THE MESSENGER
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