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Search Results for: Circadian
The ‘biome, insomnia, circadian biology, & depression. Yes, they’re all connected.
One of the most direct ways is via metabolites secreted from the ‘biome: GABA, norepinephrine, acetylcholine, serotonin, dopamine, etc. (Jacka 2018). [Patron link] Germ-free mice (ie, no ‘biome) have all sorts of behavioral abnormalities: pronounced changes in their stress responses, … Continue reading
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Easy prospects for circadian treatment of mood disorders
Interesting review showing many ways how circadian desynchronization can lead to mood disorders and some steps to fix ’em (Huhne et al., 2018) [Patron link] Circadian arrhythmia is strongly associated with a variety of mood disorders. It is known. The … Continue reading
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Fasting, circadian rhythms, and time-restricted feeding in healthy lifespan
This review by Longo & Panda was ‘fair,’ and by now you know my take on intermittent fasting (IF) vs. caloric restriction (CR). [Patron link] If you don’t, Tl;dr: since forever, all the studies on IF showed no benefits over … Continue reading
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The role of the ‘biome in insomnia, circadian disruption, and depression
Everything is connected! (Li et al., 2018) Good sleep and mood are important for health and keeping active. Keeping active is important for sleep, mood, and health. Good health is important for sleep, mood, and physical activity. “There is considerable … Continue reading
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Circadian clocks and insulin resistance
If nothing else, this article had great figures (Stenvers et al., 2018). [Patron link] Clock gene mutations, exposure to artificial light at night, disturbed sleep, shift work, social jet lag, etc., are factors that contribute to circadian disruption and insulin … Continue reading
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Consequences of circadian disruption on neurologic health and the influence of nutrients & food factors
“Impaired sleep-wake cycle, the most robust output rhythms of the circadian system, is significantly affected by neurodegenerative disorders, may precede them by decades, and may also impact their progression” (Videnovic and Zee, 2015). [Patron link] ^^^ that’s the ‘safe’ way … Continue reading
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Circadian clocks, entrainment, and health
Summary of a presentation by Orie Shafer titled “Circadian timekeeping and entrainment in neuronal clock networks.” [Patron link] From the classic Wever study, which put participants in underground dungeons to study circadian rhythms in the absence of sunlight… and showed … Continue reading
Posted in angiotensin, Bromocriptine, Cabergoline, chronopharmacology, circadian, Dopamine, melatonin, mortality, sex, sleep, Sun, vasopressin, Vitamin D
Tagged circadian rhythm, melatonin
Entrain all of your circadian clocks. Full stop.
Skipping breakfast shifts skin circadian clock and enhances UVB-induced skin aging and cancer (Wang et al., 2017)… ok, that’s not the real title of the paper, but it’s what the research showed. And it’s kind of amazing. [Patron link] Regarding … Continue reading
Posted in angiotensin, Bromocriptine, Cabergoline, cancer, chronopharmacology, circadian, depression, diabetes, Dopamine, Exercise, melatonin, muscle, Protein, sex, sleep, Sun, testosterone, vasopressin, Vitamin D
Tagged circadian rhythm
Regular circadian effects vs. effects of circadian misalignment.
Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans (Morris et al., 2015) [Patron link] “Glucose tolerance is lower in the evening and at night than in the morning.” THE FIRST FRIGGIN’ LINE! Come on … Continue reading
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Anabolic Heterogeneity Following Resistance Training: A Role for Circadian Rhythm?
YES! Resistance exercise stimulates muscle growth, strength, and functionality (Camera, 2018), although the inter-individual variability in response is hyooge. People used to think there were “responders” and “non-responders,” although now we know everyone benefits but there’s a wide spectrum. WHY? … Continue reading