There is now substantial evidence that exposure to artificial light at night (ALAN) increases the risk of breast and prostate cancer (Moore-Ede, 2018).
MOA of ALAN: circadian disruption & phase shifting, melatonin-suppression, and accelerated unsuppressed tumor growth.
Sunlight during the day is protective. Artificial light at night is harmful.
ALAN-induced melatonin-suppression and circadian disruption increases the risk for certain endocrine-sensitive cancers. While this is most blatantly manifested in shift-workers, it also holds for people who sleep with the lights on and those exposed to, for example, street lamps shining light through bedroom windows at night.
50% increased risk of breast cancer in female shift workers. Up to 200% increased risk prostate cancer in male shift workers.
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