Bimagrumab: an elusive potential inhibitor of myostatin (the muscle blocker)
Miragrebon: a beta-3 agonist, fueler of BAT thermogenesis
Tl;dr: both work. In addition to tirzepatide (or its subordinate, semaglutide), exercise in a [poly]pill may have arrived…… including UPF-free #eTRF if you are so inclined or striving for #Optimal™ jk 🙂
Effect of Bimagrumab vs Placebo on Body Fat Mass Among Adults With Type 2 Diabetes and Obesity: A Phase 2 Randomized Clinical Trial (Heymsfeld et al., 2021)
Tl;dr: we weren’t wrong about myostatin, we just didn’t have the right tools to influence it. Now, we do.
Next time someone says you can’t gain muscle and lose fat at the same time, here’s another example proving them wrrrongo (pronounced with a rolling “r”):
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