None of them have particularly great study designs, but that hasn’t prevented the buzz. Here is a summary of the strengths and weaknesses.
DiReCT (Diabetes Remission Clinical Trial): randomized. N=306, 1-year. 3-5 months ultra-low calorie weight loss diet (~850 kcal/d) followed by 2-8 weeks of guided food reintroduction and then weight maintenance counseling.
PURE (Prospective Urban Rural Epidemiology): n=135335, 7.4 years follow-up. The dreaded Food Frequency Questionnaire, although they were comparing lowest with highest quintile… I think I can accurately recall if I’ve had more than 5 servings of something today or none in the past month. They’re not asking what I had to eat August 25th 2017 for lunch.
Virta: low carb, calorie restricted. N=262, 1 year long. They had a weight maintenance control group, which is good, but it’s not hard to beat a weight maintenance control group with any diet. A low fat comparison group would’ve been more informative.
For the rest of this article including the main findings and interpretation, head over Patreon! Five bucks a month for full access. It’s ad-free and you can cancel at any time.
If you’re interested in setting up consultations with me, reach out: email@example.com.
Affiliate links: Still looking for a pair of hot blue blockers? TrueDark is offering 10% off HERE and Spectra479 is offering 15% off HERE. If you have no idea what I’m talking about, read this then this.
Join Binance and get some cryptoassets or download Honeyminer and get some Bitcoins for free!
20% off some delish stocks and broths from Kettle and Fire HERE.
If you want the benefits of ‘shrooms but don’t like eating them, Real Mushrooms makes great extracts. 10% off with coupon code LAGAKOS. I recommend Lion’s Mane for the brain and Reishi for everything else.
Join Earn.com with this link.
Start your OWN Patreon campaign!