Entrain all of your circadian clocks. Full stop.

Skipping breakfast shifts skin circadian clock and enhances UVB-induced skin aging and cancer (Wang et al., 2017)… ok, that’s not the real title of the paper, but it’s what the research showed. And it’s kind of amazing.

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Regarding skin cancer and wrinkles, there are two basic processes to focus on: proliferation and protection.

 

 

These processes don’t really overlap: you want endogenous protective mechanisms during the day, to protect against UV rays, and you don’t want to be proliferating at this time because that would increase the chances of a malignant mutation being passed on.


Conversely, at night when the risk of UV-induced DNA damage is considerably less, it’s a green light for proliferation of skin cells. This is healthy, anti-aging-like turnover of skin cells.

We’ve discussed the importance of co-entrainment of your circadian clocks in the path: sunlight in the morning to start up the central pacemaker, breakfast in the morning to co-entrain many of the peripheral clocks with the master clock, exercise to get the skeletal muscle clock on board… but now we have another reason for breakfast: to co-entrain the circadian rhythms in your skin!

Consequences of skipping breakfast, going to the gym at night, staying up late, and having a big dinner: increased risk of obesity, diabetes, cardiovascular disease, cancer, etc., etc…

In this study: skin aging and cancer.

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